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Affiliation sites de rencontre

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Figure 1: X-chromosome inactivation is initiated during female development and leads to the silencing of one of the two X chromosomes at random in eutherian mammals. The inactive state is stably propagated, thanks to epigenetic marks, leading to clonal populations of cells expressing either one or the other of the two X chromosomes. Females display cellular mosaicism for X-linked gene expression as illustrated by female calico cats that are heterozygous for an X-linked coat colour gene leading to either orange or black patches of fur. Right, Allele-specific HiC analysis in clonal neural progenitor cells: the inactive X is organised into two large mega-domains while the active X is organised into TADs and compartments.
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Video сomments (16)

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